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Ipamorelin, despite also being a short research compound, has a notably longer terminal half-life: a human pharmacokinetic study measuring dose-escalating infusions in healthy volunteers found a short terminal half-life of 2 hours for ipamorelin roughly twelve times longer than sermorelin’s

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CDC summarizes USP guidance: date an opened multi-dose vial at first puncture and discard it within 28 days.⁷ The dose count and 28-day window together require three vials for the 12-week protocol