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Week 3-4 (1 Month): With consistent weekly injections, improved diet, and regular exercise, some patients begin noticing changes in how their body processes fat

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¹⁶ Over-loss and muscle — the pooled SURMOUNT analysis shows the tail changing with time: BMI below 22 reached about 8.3% by week 72 and 14.6% in the longer 88-week SURMOUNT-4 instrument, while BMI below 18.5 remained uncommon, roughly 0.3–1.5%