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The authors further showed that the enzyme Spot14 decreases the availability of malonyl-CoA, a Fasn substrate for lipogenesis, and that Spot14- NSCs isolated by cell sorting from a knockout Spot14-CreERT2 mouse present higher proliferation than Spot14 + cells

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[36] The first step, and the rate-limiting enzyme in the salvage pathway is nicotinamide phosphoribosyltransferase (NAMPT), which produces nicotinamide mononucleotide (NMN)