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Specifically, IL-1α is constitutively produced and retained in keratinocytes, but in response to several stimuli, IL-1α is released, which is essentially a primary event of inflammation

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Microscopy From rats, at end of the experiment, the brain, liver, kidney, stomach, duodenum, jejunum, colon, rectum, lungs, and heart were fixed in 10% neutral buffered formalin (pH 7.4) at room temperature for 24 h