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This randomized controlled trial suggests that vitamin B12 supplementation may improve homocysteine levels and metabolic markers in patients with liver disease, with modest effects on liver health
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Another consideration when supplementing larger doses of Vitamin B6 as pyridoxine is the inhibiting effect on Pyridoxal-5-Phosphate (P5P), which is the natural form of Vitamin B6, so if amounts larger than 50 mg are taken per day, or if they are taken on an ongoing basis, the pills should also contain a small percentage as pyridoxal-5-phosphate to avoid the potential of causing neurological damage
made form of vitamin B12 used to treat low levels (deficiency) of this vitamin