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C32 is the second active-site cysteinyl residue of PfGrx and C88 is the third cysteinyl residue, which is in the proximity of the active site and can also undergo redox modifications 14,26,30

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Yet this naturally occurring tripeptide-copper complex has been the subject of more published research than almost any other peptide in the anti-aging and skin regeneration space, with over 100 studies spanning five decades