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In mitochondria, GABA is converted to succinate through the GABA shunt [24] and ultimately enters the tricarboxylic acid (TCA) cycle or another metabolic pathway to produce γ- hydroxybutyric acid [25,26]

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Additionally, iron chelating agents, including chloroiodohydroxyquine and its derivatives, as well as antioxidants, have shown efficacy in animal models of AD, though clinical trials are yet to be conducted (27,106,116)