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Other technologies, including eConsent, CTMS, RTSM, eTMF, and integration middleware, are less visible to participants but determine whether decentralized procedures can operate within a controlled clinical-quality environment
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In the case of pronounced absorption disorders, for example as a result of gastritis or after removal of the small intestine, in Crohn's disease, diverticulosis and the so-called blind-loop syndrome, there is a gradual decrease in the vitamin B12 store in the liver, which can turn into a manifest vitamin B12 deficiency