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Corticosteroid Injections Corticosteroids are commonly used for short-term pain relief in OA, but repeated injections may worsen cartilage degeneration

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The animals were placed in an induction chamber with an oxygen-enriched environment, with the initial induction concentration set at 4%–5% isoflurane, until deep anesthesia signs such as loss of the righting reflex appeared, after which maintenance was initiated