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62 Additionally, GSTs contribute to the regulation of cellular redox balance by modulating reactive oxygen species and reactive nitrogen species levels through the conjugation of GSH to oxidized molecules

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Metabolic Perturbation# While increased NAD+ is generally considered beneficial, the broader metabolic consequences of NNMT inhibition -- including effects on polyamine metabolism, one-carbon metabolism, and other SAM-dependent pathways -- have not been systematically evaluated

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