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Low glutathione S-transferase P1 levels are associated with higher mortality in COVID-19 patients, and high levels of glutathione S-transferase P1 possibly offer protection for cellular redox reactions in severe COVID-19 infection, preventing deterioration especially in patients with co-morbidities like diabetes (Kumar D.S

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PGE2 increases pro-inflammatory (M1-like) microglia and astrocytes, resulting in increased IL-6, TNF-α, and iNOS levels (Sanjay et al., 2022)