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In vitro studies may evaluate compound-associated activity using predefined molecular markers, cell-based assays, receptor systems, and comparative analytical methods

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Excellent dietary sources include : Meat and poultry : beef, lamb, pork, chicken, and particularly organ meats such as liver Fish and shellfish : salmon, trout, tuna, sardines, mackerel, and clams (which are exceptionally rich in B12) Dairy products : milk, cheese, and yoghurt Eggs : particularly the yolk For patients following plant-based diets or those with significantly reduced appetite, fortified foods can provide B12, including fortified breakfast cereals, plant-based milk alternatives, nutritional yeast, and some meat substitutes