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Nevertheless, the GSTM1*0/GSTT1*0 genotype has been shown to be a potential genetic risk factor for essential hypertension (40), and it has been reported that genetic loss of the GSTT1 enzyme is an independent and powerful predictor of premature vascular morbidity and death in individuals with type 2 diabetes (41)

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As with most supplements, results can be gradual and noticeable over time