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When pretreated with antibodies to integrins alpha 1 and beta 1, MSC failed to produce an increase of VEGF, which indicated that the effects of GHK on secretion of trophic factors by MSC involve the integrin cellular pathway [30]

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Another direct consequence of the G-E theory is that lesions are biochemically variable and that some lesions can develop with minimal estrogen concentrations, as suggested by the occurrence of endometriosis after menopause or after hysterectomy with removal of ovaries