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Biochemical Basis of Cellular Aging and Oxidative Stress Reactive Oxygen Species (ROS) continuously attack DNA, lipids, and proteins

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Lactate and lactylation Lactate, as a metabolic product of glycolysis, was once considered to be merely a harmful metabolic byproduct produced under hypoxic conditions, but an increasing number of studies have demonstrated that lactate plays a crucial role in the regulation of whole-body metabolism [13]