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In addition, we discuss some limitations and challenges that limit the translation of ginsenosides into clinical trials, such as limited bioavailability, variability in pharmacokinetic behavior, the lack of robust, well-designed clinical trials, and emerging strategies to overcome these challenges, such as drug delivery systems, structural optimization, and target identification
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In 3 clinical trials on over 350 constipated adults, they improved 47% of all cases and up to 87% of those due to nerve damage [8, 9, 10]
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